The GLobal Epidemic and Mobility modeler (GLEaM) is a model developed by the Indiana University Center for Complex Networks and Systems Research and the Complex Networks and Systems Group at the ISI Foundation (Turin, IT). GLEaM is described as "GLEaM is a discrete stochastic epidemic computational model based on a meta-population approach in which the world is defined in geographical census areas connected in a network of interactions by human travel fluxes corresponding to transportation infrastructures and mobility patterns."

The gleamviz.org site provides updated results from the GLEaM 2.0 simulation engine based on the H1N1 2009 outbreak.  GLEaM incorporates air travel, population data, and also "includes the effect of short range mobility patterns corresponding to ground movements and commuting patterns."

Predictions for the H1N1 outbreak made by GLEaM appear to be tracking well with the Northwestern ESAM simulation project.